About THRIVE 131

About Sickle Cell Disease

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About Sickle Cell Disease


Overview
Symptoms & Treatment


Red blood cells are responsible for carrying oxygen throughout the body. In a person living with sickle cell, some red blood cells change shape and become sickled, or banana shaped. The sickling process begins with hemoglobin, the part of the red blood cell that carries oxygen. When cells sickle, they can break down and there are fewer red blood cells to carry oxygen to all parts of the body. This can cause serious, long-term complications. Sickle cell is always causing damage in the body, even when pain might not be felt.

STATS

It is estimated that:

100K

Americans affected
by SCD

1 in 365

Black or African-American babies are born with SCD

~20%

of people living with SCD usually receive their care in an emergency room

SDC is a genetic, hereditary disease

Requires medical diagnosis

Lab tests or imaging always required

Chronic: lifelong

For informational purposes only. Consult your local medical authority for advice.
Content ources:  National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention

SYMPTOMS

Pain areas: in the joints

Pain types: can be sudden in the chest, can include vaso-occlusive crises (VOCs)

Whole body: dizziness, fatigue, low oxygen in the body, or malaise

Urinary: inability to make concentrated or dilute urine or blood in urine

Also common: abnormal breakdown of red blood cells, delayed development, inflamed fingers or toes, pallor, shortness of breath, or yellow skin and eyes

A vaso-occlusive crisis (VOC) is defined as an acute episode of pain that:

  • has no medically determined cause other than a vaso-occlusive event, and
  • results in a visit to a medical facility (hospitalization, emergency department, urgent care center, outpatient clinic, or infusion center), or results in a remote contact with a healthcare provider; and
  • requires parenteral narcotic agents, parenteral non-steroidal anti-inflammatory drugs (NSAIDS), or an increase in treatment with oral narcotics.

TREATMENT

Management of sickle cell is usually aimed at avoiding pain episodes, like VOCs, relieving symptoms and preventing complications. Treatments might include medications and blood transfusions. Vaccinations and penicillin can be used to help prevent life-threatening infections.

For informational purposes only. Consult your local medical authority for advice. Content source: Mayo Clinic

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